• Journal of Biomedical Research is a peer reviewed open access journal dedicated to publishing high-quality research in all areas of the biological and medical sciences.
Current Issue             Journal of Biomedical Research--2017, 31(4)
PERSPECTIVE
Cost and value in medical education: the role of statistical process control
Kieran Walsh

J Biomed Res 2017;31(4):277-278.   doi:10.7555/JBR.31.20160086
REVIEW ARTICLES
Monitoring cerebral ischemia during cerebrovascular surgery
Hong Zhang,Lingzhong Meng,Russ Lyon,Dong-Xin Wang
Patients undergoing intracranial cerebrovascular surgery under general anesthesia are at risk of cerebral ischemia due to the nature of the surgery and/or the underlying cerebrovascular occlusive disease. It is thus imperative to reliably and continuously monitor cerebral perfusion during this type ...more>>
J Biomed Res 2017;31(4):279-282.   doi:10.7555/JBR.31.20150106
Acute-on-chronic liver failure: recent update
Azeem Alam,Ka Chun Suen,Daqing Ma
Acute on chronic liver failure (ACLF) was first described in 1995 as a clinical syndrome distinct to classic acute decompensation. Characterized by complications of decompensation, ACLF occurs on a background of chronic liver dysfunction and is associated with high rates of organ failure and signifi...more>>
J Biomed Res 2017;31(4):283-300.   doi:10.7555/JBR.30.20160060
ORIGINAL ARTICLES
Thalamic paramagnetic iron by T2* relaxometry correlates with severity of multiple sclerosis
Eva Baranovicova,Ema Kantorova,Dagmar Kalenska,Lucia Lichardusova,Michal Bittsan- sky,Dusan Dobrota
Iron can contribute to the pathogenesis and progression of multiple sclerosis (MS) due to its accumulation in the human brain. We focus on the thalamus as an information transmitter between various subcortical and cortical areas. Thalamic iron seems to follow different rules than iron in other deep ...more>>
J Biomed Res 2017;31(4):301-305.   doi:10.7555/JBR.31.20160023
(+)-Borneol is neuroprotective against permanent cerebral ischemia in rats by suppressing production of proinflammatory cytokines
Lei Chang,Chun-Yu Yin,Hai-Yin Wu,Bin-Bin Tian,Yan Zhu,Chun-Xia Luo,Dong-YaZhu
Stroke is one of the leading causes of disability and death globally. It occurs when a major artery is occluded in the brain and leads to death of cells within the injured tissue. (+)-Borneol, a simple bicyclic monoterpene extracted from traditional Chinese medicine, is widely used in various types ...more>>
J Biomed Res 2017;31(4):306-314.   doi:10.7555/JBR.31.20160138
Clinical application of simultaneous detection of cystatin C, cathepsin S, and IL-1 in classification of coronary artery disease
Ling Yan,Shuang Ding,Bing Gu,Ping Ma
Cystatin C, cathepsin S, and IL-1 are three important biomarkers of atherosclerosis. Previous studies emphasized the relationship between individual biomarkers in coronary artery disease (CAD) patients and severity of atherosclerostic lesions of the coronary arteries, while combined cystatin C, cath...more>>
J Biomed Res 2017;31(4):315-320.   doi:10.7555/JBR.31.20150152
Safety, immunogenicity, and cross-species protection of a plasmid DNA encoding Plasmodium falciparum SERA5 polypeptide, microbial epitopes and chemokine genes in mice and olive baboons
Nyamongo Onkoba,Ruth M. Mumo,Horace Ochanda,Charles Omwandho,Hastings S. Ozwara,Thomas G. Egwang
Incorporation of biomolecular epitopes to malarial antigens should be explored in the development of strain- transcending malarial vaccines. The present study sought to determine safety, immunogenicity and cross-species efficacy of Plasmodium falciparum serine repeat antigen 5 polypeptide co-express...more>>
J Biomed Res 2017;31(4):321-332.   doi:10.7555/JBR.31.20160025
Farnesol inhibits development of caries by augmenting oxygen sensitivity and suppressing virulence-associated gene expression in Streptococcus mutans
Li Cao,Zhen-zhen Zhang,Shuang-bo Xu,Ming Ma,Xin Wei
Streptococcus mutans is a primary etiological agent of dental caries. Farnesol, as a potential antimicrobial agent, inhibits the development of S. mutans biofilm. In this study, we hypothesized that farnesol inhibits caries development in vitro and interferes with biofilm formation by regulating vir...more>>
J Biomed Res 2017;31(4):333-343.   doi:10.7555/JBR.31.20150151
The effect of sunblock against oxidative stress in farmers: a pilot study
Yong-Dae Kim,Dong-Hyuk Yim,Sang-Yong Eom,Ji Yeoun Lee,Heon Kim
Farmers are frequently exposed to ultraviolet (UV) radiation which causes various diseases by inducing oxidative stress. This study aimed to assess the effects of sunblock on oxidative stress in the body. Eighty-seven farmers were divided into two groups: those who wore sunblock for five days and th...more>>
J Biomed Res 2017;31(4):344-349.   doi:10.7555/JBR.31.20160092
Moringa oleifera-based diet protects against nickel-induced hepatotoxicity in rats
Oluyomi Stephen Adeyemi,Cincin Sokolayemji Aroge,Musbau Adewumi Akanji2
Multiple health-promoting effects have been attributed to the consumption of Moringa oleifera leaves, as part of diet without adequate scientific credence. This study evaluated the effect of M. oleifera-based diets on nickel (Ni) - induced hepatotoxicity in rats. Male rats assigned into six groups w...more>>
J Biomed Res 2017;31(4):350-357.   doi:10.7555/JBR.31.20160051
Effects of bisphenol compounds on the growth and epithelial mesenchymal transition of MCF-7 CV human breast cancer cells
Ji-Youn Kim,Ho-Gyu Choi,Hae-Miru Lee,Geum-A Lee,Kyung-A Hwang,Kyung-Chul Choi
Bisphenol-A (BPA) has been considered as an endocrine disrupting chemical (EDC) because it can exert estrogenic properties. For bisphenol-S (BPS) and bisphenol-F (BPF) that are BPA analogs and substitutes, their risk to estrogendependent cancer has been reported rarely compared with the numerous cas...more>>
J Biomed Res 2017;31(4):358-369.   doi:10.7555/JBR.31.20160162
CASE REPORT
Herpes zoster in breast cancer: a case report
Mohammad Darvishi,Narges Vasei
There is little information on herpes zoster infection in breast cancer patients as a complication during adjuvant chemotherapy. We report a case of herpes zoster in a 65-year-old woman presented with low grade fever and vital signs together with skin symptoms such as severe edema, irritation and it...more>>
J Biomed Res 2017;31(4):370-372.   doi:10.7555/JBR.31.20170009
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