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Yong-Dae Kim,Dong-Hyuk Yim,Sang-Yong Eom,Ji Yeoun Lee,Heon Kim.Journal of Biomedical Research,2017,31(4):344-349
The effect of sunblock against oxidative stress in farmers: a pilot study
Received:August 02, 2016  Revised:August 23, 2016
DOI10.7555/JBR.31.20160092
Keywordsfarmers, ultraviolet rays, sunscreening agents, oxidative stress, total antioxidant capacity
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AuthorInstitution
Yong-Dae Kim Center for Farmers ' Safety and Health, Chungbuk National University Hospital, Cheongju, Republic of Korea;Department of Preventive Medicine, College of Medicine, Chungbuk National University, Cheongju, Republic of Korea
Dong-Hyuk Yim Center for Farmers ' Safety and Health, Chungbuk National University Hospital, Cheongju, Republic of Korea;Department of Preventive Medicine, College of Medicine, Chungbuk National University, Cheongju, Republic of Korea
Sang-Yong Eom Center for Farmers ' Safety and Health, Chungbuk National University Hospital, Cheongju, Republic of Korea;Department of Preventive Medicine, College of Medicine, Chungbuk National University, Cheongju, Republic of Korea
Ji Yeoun Lee Center for Farmers ' Safety and Health, Chungbuk National University Hospital, Cheongju, Republic of Korea;Department of Dermatology, College of Medicine, Chungbuk National University, Cheongju, Republic of Korea
Heon Kim Center for Farmers ' Safety and Health, Chungbuk National University Hospital, Cheongju, Republic of Korea;Department of Preventive Medicine, College of Medicine, Chungbuk National University, Cheongju, Republic of Korea
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Abstract
      Farmers are frequently exposed to ultraviolet (UV) radiation which causes various diseases by inducing oxidative stress. This study aimed to assess the effects of sunblock on oxidative stress in the body. Eighty-seven farmers were divided into two groups: those who wore sunblock for five days and those who did not. The total antioxidant capacity (TAC) in urine, which is an antioxidant indicator, and 8-hydroxy-2-deoxyguanosine (8-OHdG) levels in urine, an oxidative stress indicator, were measured. The urinary TAC of sunblock users was significantly higher than that of non-users, but urinary 8-OHdG levels were not significantly different. Even after adjustment for potential confounders, urinary TAC was found to be markedly increased with sunblock usage. These results suggest that sunblock is effective in preventing oxidative stress among farmers. In addition, they show that urinary TAC can be used as a good effect marker of oxidative stress caused by UV exposure.
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