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Guanglei Wang,Su Liu,Gongjian Liu.Journal of Biomedical Research,2011,25(3):191-196
Effects of infusion of different fluids during controlled hypotension on gastric intramucosal pH and postoperative gastroenterological function
  
DOI£º10.1016/S1674-8301(11)60025-0
Keywords£ºhemodilution, controlled hypotension, gastric mucosa
Grant Program£º
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AuthorInstitution
Guanglei Wang Department of Anesthesiology, the Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu , China
Su Liu Department of Anesthesiology, the Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu , China
Gongjian Liu Department of Anesthesiology, the Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu , China
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Abstract £º
      The present study was aimed to investigate the effects of infusion of different fluids combined with control-led hypotension on gastric intramucosal pH (pHi) and postoperative gastrointestinal function in patients undergo-ing hepatocarcinoma surgery. Forty-five patients (ASA¢̣) scheduled for surgical resection of hepatocarcinoma undergoing controlled hypotension were randomly assigned to three groups and received infusion of 20 mL/kg Ringer¡¯s solution (R group), 6% HAES(H group) or 6% Voluven group (W group). Intragastric PgCO2, pHi, he-matocrit and hemoglobin were measured. The significant decrease of pHi and increase of PgCO2 were produced at 1 and 2 h after controlled hypotension in the R group (P < 0.05 or P < 0.01). The time of bowel movement af-ter operation was shorter in the W group than the R group. Meanwhile, we also did not find obvious difference in blood gas indexes among the three groups. The infusion of HAES and Voluven during controlled hypotension could improve gastrointestinal perfusion and accelerate the recovery of postoperative gastrointestinal function.
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