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Duraisamy Gomathi,Manokaran Kalaiselvi,Ganesan Ravikumar,Dominic Sophia,Velliyur Kanniappan Gopalakrishnan,Chandrasekar Uma.Journal of Biomedical Research,2012,26(4):295-302
Secondary metabolite credentials of Evolvulus alsinoides by high performance thin layer chromatography (HPTLC)
Received:November 10, 2011  
DOI10.7555/JBR.26.20110128
KeywordsEvolvulus alsinoides, high performance thin layer chromatography (HPTLC), secondary metabolites, convolvulaceae
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Duraisamy Gomathi Department of Biochemistry, Karpagam University, Coimbatore , India
Manokaran Kalaiselvi Department of Biochemistry, Karpagam University, Coimbatore , India
Ganesan Ravikumar Department of Biochemistry, Karpagam University, Coimbatore , India
Dominic Sophia Department of Biochemistry, Karpagam University, Coimbatore , India
Velliyur Kanniappan Gopalakrishnan Department of Biochemistry, Karpagam University, Coimbatore , India
Chandrasekar Uma Department of Biochemistry, Karpagam University, Coimbatore , India
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Abstract
      Plants and plant-based products are the bases of many modern pharmaceuticals that are current in use today for various diseases. The aim of the study was to investigate the biochemical constituents and high performance thin layer chromatography (HPTLC) finger printing of the ethanolic extract of Evolvulus alsinoides. Phytochemi-cal screening was done by standard procedures and HPTLC method was also established to analyze alkaloids, fla-vonoids and phenolic compounds from the ethanolic extract of Evolvulus alsinoides. Preliminary phytochemical screening showed that ethanol extracted more secondary metabolites than other solvents. HPTLC fingerprinting analysis showed the presence of various alkaloids, flavonoids and phenols (quercetin) in the ethanolic extract. It can be concluded that Evolvulus alsinoides may serve as a source of potent antioxidants that may be used in the prevention of various diseases such as cancer, diabetes and cardiovascular diseases due to the presence of phenolic compounds. HPTLC finger print of Evolvulus alsinoides may be useful in the differentiation of the species from adulterants and act as a biochemical marker for this medicinally important plant in the pharmaceutical industry and plant systematic studies.
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