• Journal of Biomedical Research is a peer reviewed biomedical journal dedicated to publishing high-quality research in all areas of the biological and medical sciences.
Current Issue             Journal of Biomedical Research--2013, 27 (2)     ,2013
Simulation-a new educational paradigm?
Mojca Konia,Aubrey Yao
Simulation is a modern educational tool that has recently gained in the field of medical education. The use of simulation continues to expand, and studies evaluating the effectiveness of simulation-based medical education are ongoing. The history of medical education and adult educational theory are...more>>
J Biomed Res 2013;27(2):75-80.   doi:doi:10.7555/JBR.27.20120107
Medical simulation-based education improves medicos' clinical skills
Zhaoming Wang,Qiaoyu Liu,Hai Wang
Clinical skill is an essential part of clinical medicine and plays quite an important role in bridging medicos and physicians. Due to the realities in China, traditional medical education is facing many challenges. There are few op-portunities for students to practice their clinical skills and their...more>>
J Biomed Res 2013;27(2):81-84.   doi:doi:10.7555/JBR.27.20120131
Development of Leishmania vaccines: predicting the future from past and present experience
Joshua Muli Mutiso,John Chege Macharia,Maria Ndunge Kiio,James Maina Ichagichu,Hitler Rikoi,Michael Muita Gicheru
Leishmaniasis is a disease that ranges in severity from skin lesions to serious disfigurement and fatal systemic infection. Resistance to infection is associated with a T-helper-1 immune response that activates macrophages to kill the intracellular parasite in a nitric oxide-dependent manner. Conver...more>>
J Biomed Res 2013;27(2):85-102.   doi:doi:10.7555/JBR.27.20120064
Prevalence and trends of aminoglycoside resistance in Shigella worldwide, 1999-2010
Bing Gu,Xing Ke,Shiyang Pan,Yan Cao,Ling Zhuang,Rongbin Yu,Huimin Qian,Genyan Liu,Mingqing Tong
Shigellosis causes diarrheal disease in humans in both developed and developing countries, and multi-drug resistance in Shigella is an emerging problem. Understanding changing resistance patterns is important in de-termining appropriate antibiotic treatments. This meta-analysis systematically evalua...more>>
J Biomed Res 2013;27(2):103-115.   doi:doi:10.7555/JBR.27.20120125
Lactobacillus isolates from healthy volunteers exert immunomodulatory effects on activated peripheral blood mononuclear cells
Keyi Sun,Chao Xie,Donghua Xu,Xiaofan Yang,James Tang,Xiaohui Ji
As probiotics in the gut, Lactobacilli are believed to play important roles in the development and maintenance of both the mucosal and systemic immune system of the host. This study was aimed to investigate the immuno-modulatory function of candiate lactobacilli on T cells. Lactobacilli were isolate...more>>
J Biomed Res 2013;27(2):116-126.   doi:doi:10.7555/JBR.27.20120074
Etiological risk factors for subfertility among Palestinian women in Gaza
Mahmoud Mohammed Sirdah,Abdelnasser Kassem Abushahla,Bahaa Yousif Ghalayeni,Ahmed Gamel Aburamadan
The inability to procreate is frequently considered a personal tragedy and a hardship for couples, impacting on the entire family and even the local community. In Gaza strip, Palestine, there has been no study on etiological risk factors for subfertility. The present study aimed to identify risk fac...more>>
J Biomed Res 2013;27(2):127-134.   doi:doi:10.7555/JBR.27.20120104
Low dose bisphenol A impairs spermatogenesis by suppressing reproductive hormone production and promoting germ cell apoptosis in adult rats
Pengpeng Jin,Xiaoli Wang,Fei Chang,Yinyang Bai,Yingchun Li,Rong Zhou,Ling Chen
Bisphenol A (BPA), an estrogenic chemical, has been shown to reduce sperm count; however, the underlying mechanisms remain unknown. Herein, we show that oral administration of BPA (2 μg/kg) for consecutive 14 days in adult rats (BPA rats) significantly reduced the sperm count and the number of germ ...more>>
J Biomed Res 2013;27(2):135-144.   doi:doi:10.7555/JBR.27.20120076
Integrated DNA-based/biochemical screening for early diagnosis of multiple endocrine neoplasia type 2A (MEN2A)
Qin Cui,Wen Wang,Zhenzhen Fu,Xin Shao,Zhihong Zhang,Mei Zhang,Xianxia Ju,Kunlin Wang,Jiawei Chen,Hongwen Zhou
Multiple endocrine neoplasia type 2A (MEN2A), a subtype of MEN2, is characterized by medullary thyroid cancer, pheochromocytoma, and primary hyperparathyroidism. A Han Chinese pedigree with MEN2A was inves-tigated following confirmation of the proband's diagnosis by pathological findings and DNA/bio...more>>
J Biomed Res 2013;27(2):145-150.   doi:doi:10.7555/JBR.27.20120121
Immediate and delayed micro-tensile bond strength of different luting resin cements to different regional dentin
Abdelraheem Mohamed Ali,Ibrahim Mohamed Hamouda,Mohamed Hamed Ghazy,Manal Mohamed Abo-Madina
We sought to evaluate immediate and delayed micro-tensile bond strength of Panavia F2.0 and Multilink Sprint resin cement to superficial, deep and cervical dentin. Thirty-six freshly extracted non-carious human molars were sectioned in the mesiodistal direction to expose three different dentin regio...more>>
J Biomed Res 2013;27(2):151-158.   doi:doi:10.7555/JBR.27.20120028
Late anastomotic perforation following surgery for gastric neuroendocrine tumor complicated by perforated duodenal ulcer: a case report
Jun Han,Zhenyu He
Neuroendocrine tumors (NETs) are a group of neoplasms that are characterized by the secretion of a variety of hormones and diverse clinical syndromes. NETs are considered to be rare, but the incidence of NETs has in-creased rapidly in recent years. NETs provide a clinical challenge for physicians be...more>>
J Biomed Res 2013;27(2):159-162.   doi:doi:10.7555/JBR.27.20110109
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